Afamelanotide · MT-1 · NDP-MSH · [Nle4-D-Phe7]-α-MSH
| Classification | Linear tridecapeptide; synthetic α-MSH analog |
|---|---|
| Amino acid sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
| Short notation | Ac-SYSNle-EH-DPhe-RWGKPV-NH2 |
| Molecular formula | C78H111N21O19 |
| Molecular weight | 1646.85 g/mol |
| CAS number | 75921-69-6 |
| Solubility | Soluble in water and bacteriostatic water. |
| Reported half-life | The Nle4 and D-Phe7 substitutions confer substantially greater resistance to enzymatic degradation than native α-MSH. |
International orders have a 3-vial minimum per product. Case pricing shown is international; US warehouse case pricing may differ and is shown at checkout.
A linear α-MSH analog with norleucine and D-phenylalanine substitutions that increase potency and stability. Unlike Melanotan 2, it is selective for MC1R rather than broadly active across melanocortin receptors.
The following describes contexts in which this compound appears in published laboratory literature. Nothing here is a claim of efficacy, safety, or suitability for any use in humans or animals.
| Lyophilized powder | Store lyophilized powder at -20 °C, sealed and protected from light. This compound is light- and oxidation-sensitive. |
|---|---|
| After reconstitution | Store at 2–8 °C in light-protective packaging; use within approximately 4 weeks. Avoid repeated freeze-thaw cycles. |
| Shipping | Ships at ambient temperature in light-protective packaging. |
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| Vial | 1 vial (US) | 3 vials (Intl) | Case of 5 | Case of 10 | Stock |
|---|---|---|---|---|---|
| 10mg | — | $120 | $155 | $220 | International |
$20 flat USA shipping · solutioning available at $10/vial · Denver stock ships within 1 business day of order confirmation.